In a world transformed by artificial intelligence, the education sector faces the challenge of reinventing itself to remain relevant and accessible. This keynote will explore two essential dimensions: how to foster educational innovation to adapt to the rapid changes driven by AI, and how to leverage this technology as a tool to design disruptive pedagogical solutions. Additionally, it will examine the pivotal role of think tanks, foundations, and academic institutions in supporting and accelerating this process through strategic collaborations and effective resources. Inspiring examples from the WISE community will be shared, showcasing innovative solutions implemented in the Global South and demonstrating how global partnerships can make a difference in local contexts.